Livivo: Innovative nutraceutical-biofactor for fatty liver

The liver is one of the most complex, important, and neglected organs in the body. The liver performs over 500 functions for the body and is one of the body’s best defenses against damage from infection, filtering away of toxic substances, storage of excess energy (glucose) and other vital metabolic functions. The health of the liver often reflects a person’s overall health.

Eating excess calories causes fat to build up in the liver leading to non-alcoholic fatty liver disease (NAFLD) as the liver does not process and break down fats as it normally should. NAFLD is a global epidemic that threatens human health. A growing health problem that affects more than one billion people worldwide. NAFLD develops silently without signs or symptoms. If it is not effectively treated, it may progress to cirrhosis, which may lead to liver failure and liver cancer as well as to cardiovascular diseases.

While lifestyle changes such as diet and exercise can help prevent and manage NAFLD, there is still no accepted effective drug treatment for NAFLD. The basis for an effective treatment of NAFLD is the identification of various components that intervene in each of the damaging processes to prevent the progression of the disease.

Despite the magnitude of the problem there is an absence of solutions from both the pharmaceutical or nutraceutical industries.

Recent research has identified several bioactive nutrients and compounds that may help slow or even reverse the progression of NAFLD. Livivo™, an innovative nutraceutical-biofactor developed by Galmed Pharmaceuticals, is at the forefront of such developments. Livivo™ stands out from its peers in the nutraceutical market as it inherits the discipline and scientific rigor of a pharmaceutical company to provide a researched answer to an unmet need.

Livivo™️'s proprietary formula is based on 25 years of published scientific research that has identified specific compounds and micronutrients that may interfere with the progression of NAFLD. Livivo™ is designed to be an indulgence that blends with everyday life, making it easy and convenient to incorporate into a healthy lifestyle. It targets the liver with a blend of bioactive nutrients delivered to the liver in the form of edible bites and crystals.

Livivo™️'s line of products includes Peanut Butter Bites and Chocolate Crystals, both designed to be taken twice daily. These products are formulated with Steamchol™, a proprietary nutraceutical-biofactor that combines stearic acid and cholic (bile) acid to help the body digest fat from foods.

The connection between bile acids and NAFLD has long been recognized by leading liver specialists and journals. A large body of evidence from clinical as well as preclinical studies demonstrates that bile acid homeostasis is disrupted in patients with NAFLD. Cholic acid, one of the two key bile acids in the liver, is necessary for proper digestion, absorption, and toxin removal which allow the liver to work normally.

Bile helps with digestion. It breaks down fats into fatty acids, which can be taken into the body by the digestive tract, it helps absorb dietary fats, fat-soluble vitamins, and other nutrients.  As well as eliminating cholesterol from the body.

Unlike many supplements that are good in concept but not absorbed correctly and lose their efficacy, Livivo™ differs dramatically. Its active component, Steamchol™ is formulated using the latest in micro-encapsulation technology, allowing Livivo™ to be delivered to where it is most needed, the liver.

Livivo™️'s dynamic team includes scientists, clinicians, nutritionists, and food technologists. They work together to allow Livivo™️ to build and adapt their product to satisfy their product's regulatory and commercial needs for each market that our partners know best.  

Livivo™️'s targeted approach represents a promising solution for the millions of people suffering from fatty liver, who may benefit from a liver targeted supplementation program to support liver health. While lifestyle changes such as diet and exercise are the primary means of preventing and managing NAFLD, they are not always sufficient. Targeted supplementation programs like Livivo™ may help fill in the gaps and provide additional support for liver health. As the prevalence of NAFLD continues to rise, innovative solutions like Livivo™ represent an important step forward in the prevention and management of this serious health problem.